Welcome to KBase

The knowledge creation and discovery environment for systems biology.

GET STARTED
Discover more with a powerful, open science data platform

Discover more with a powerful, open science data platform

Developed for bench biologists and bioinformaticians, The Department of Energy Systems Biology Knowledgebase (KBase) is a software and data science platform designed to meet the grand challenge of systems biology: predicting and designing biological function.

TECHNOLOGY
TECHNOLOGY
Data Science Platform
Analyze private data in the context of public data with leading open-source tools powered by high-performance computing.
Free and Easy to Use
Create a free account and begin exploring what KBase can do for your research.
COMMUNITY
COMMUNITY
Reproducible Science
Capture your discoveries in a Narrative, an interactive digital notebook that can be shared with the world.
Collaborative Research
Manage data access and sharing across your project, laboratory, or institution.
STEWARDSHIP
STEWARDSHIP
Control Your Data
Keep data private until you’re ready to share with the public.
Data Tracking
Version-controlled apps and data provenance allow you to track your data.
Why KBase?

Why KBase?

KBase is the first large-scale data science platform that enables users to upload their own data, analyze it alongside collaborator and public data, build increasingly realistic models, and share and publish reproducible workflows and conclusions.

KBase integrates data and tools in a unified graphical interface. Users no longer need to do analyses across multiple systems in order to create and run sophisticated systems biology workflows. KBase allows users to perform large-scale analyses and combine multiple lines of evidence to model plant and microbial physiology and community dynamics.

Getting started with KBase
Getting started with KBase

Getting started with KBase

CREATE AN ACCOUNT
Read about KBase in Nature Biotechnology*

Read about KBase in Nature Biotechnology*

For a comprehensive overview of KBase and its scientific impact, this publication details the unique features and infrastructure of the KBase platform through several scientific use cases.

*How to cite: Arkin AP, Cottingham RW, Henry CS, et al. KBase: The United States Department of Energy Systems Biology Knowledgebase. Nature Biotechnology. 2018;36: 566. doi: 10.1038/nbt.4163
Looking for information on tools and resources?

Looking for information on tools and resources?

Check out KBase Documentation for our Getting Started guide and information on tools in the App Catalog. KBase is a fully open source software project available on GitHub.

Appdev maintenanceAppdev maintenance Oct 29

We will be performing system maintenance on appdev.kbase.us on Thursday, October 29, 2020, from 1pm-5pm PDT (3pm-7pm CDT).  All of appdev.kbase.us will be unavailable or unstable during parts of this window.