Soil Microbiome SFA

A systems-level approach to understanding  microbial response to changing soil conditions

The Phenotypic Response of the Soil Microbiome to Environmental Perturbations (a.k.a. Soil Microbiome) Science Focus Area, led by Dr. Kirsten Hofmockel at Pacific Northwest National Laboratory (PNNL) uses cross-scale empirical and modeling experiments to identify phenotypic elements underpinning community metabolism, metaphenomes expressed under drought, and the implications for carbon use efficiency.

Collaborative Development Projects

Starting Fall 2021 – Omics-enabled global gapfilling (OMEGGA) for phenotype-consistent metabolic network reconstruction of microorganisms and communities

Additional Information

Meet the Members

SFA Principal Investigators: Kirsten S. Hofmockel1
KBase Contact: Chris Henry2,3, Janaka Edirisinghe2,3
Lead Developers: William Nelson1, Hyun-Seob Song4
Project Team: Jason McDermott1, Aimee Kessell4
Affiliations: 1Pacific Northwest National Laboratory, 2Argonne National Laboratory, 3KBase, 4University of Nebraska-Lincoln


  • PNNL Soil Microbiome SFA Project Website – Advancing our understanding of how soil microbial communities respond to—and affect—changing environmental conditions
  • GitHub Repository – coming soon
System maintenance May 25

We will be performing system maintenance on Wednesday, May 25, from 2-4pm PDT (4-6pm CDT)., compute jobs, and may be unavailable or unstable for parts of this time.

We do not anticipate any interruption to